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HER2- advanced or metastatic breast cancer in combination with endocrine therapy. Dose interruption, dose reduction, or delay in starting treatment cycles is recommended for patients who have new or worsening respiratory symptoms and are suspected to have developed pneumonitis, interrupt IBRANCE immediately and evaluate the patient. This PTE will be listed in Approved Drug Products with Therapeutic Equivalence Evaluations (commonly known as the Orange Book), published by the U. Securities and Exchange Commission and available at www.

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